Tuesday, 25 May 2010

Word to the wise

If you are a microbiologist or evolutionary biologist don't read Virolution by Frank Ryan.  It's pop science repetitive vomit.  If you have had any sort of genetics learning it becomes very boring very quickly.  Pity because I thought it would be good.  Now Im not a great decryer of pop science - I just like well written science books that dont read like a massive ego boost on the authors behalf.   For a really cool pop science book on microbiology read these books - I have read them and they are good.  Yes I am a scientist - so you know they're good.  The bold ones are written by author's I just could kiss - they are just that good.

10 Good popular science books (emphasis on the micro side)
  1. The Coming Plague - Laurie Garrett (Awesome book - been out a while but still very, very good.  It is on the long side but dont let that stop you very good book)
  2. Parasite Rex - Carl Zimmer (one of my favourite pop sci books - really well written and the parasites are just cool)
  3. The Seven Daughters of Eve - Bryan Sykes
  4. Stiff - Mary Roach
  5. The Doctor's Plague - Sherwin B. Nuland
  6. Plague's Progress - Arno Karlen
  7. Viruses vs Superbugs - Thomas Hausler
  8. Guns, Germs and Steel - Jared Diamond
  9. The Hot Zone - Richard Preston ( Very, very interesting book)
  10. The Dark Lady of DNA - Brenda Maddox
There are more - I just have to remember which ones I have read - there is a really good one about antibiotics whose name escapes me.  I will return :)

S.

Tuesday, 18 May 2010

Eww look her eyelashes are fluttering!

Yes dear readers - your very absent blogger has returned. So what have I done since I last posted? Got married, promptly ran away to a faraway land, started a new work contract and moved house. Not much really. I have been reading - lots of science guff but also a few books as well. 

The Immortal Life of Henrietta Lacks by Rebecca Skloot

Moral corruption, theft of bodily tissues and the multi-million dollar business that is of the world that is HeLa. HeLa cells are quite frankly God's gift to this world - they have enabled a very large amount of life saving science to proceed eg Polio vaccine, cancer research etc. None of it would have happened if Henrietta Lacks had not contracted the HPV virus which caused cervical cancer. The tumour grew wildly and spread throughout her body eventually killing her. The short and the long of it was that the doctor who first cultivated the cells took them from her pathology without patient permission or any sort of informed consent. He then proceeded to send the cells around the world for a fee. Did I mention this occurred at John Hopkins? It is a really, really interesting book about the life and death and immortal cells of Henrietta Lacks. Oh and the really slack, pass the buck culture that has occurred within the Science community at large and at John Hopkins and Invitrogen in particular.

PS thank you darling man for my bday present.

Patient Zero by Jonathan Maberry

Who doesnt love a bit of Zombie gore and biowarefare? I liked it - good for reading on a plane - which is what I did. It is all about our main character chasing, killing and generally blowing up the terrorists and their pet zombies. Not too hard out Im in a thinking mood kinda book - but we all need a blow em up book every now and then.


I like Tess Gerritsen.  I like her slight fluff style of murder thriller novels.  I liked this one too.  It has nuns, blood and gore, and dirty secrets.  Dr Isles and Detective Rizzoli on the case.   Good for killing time.

Eww and I have been watching some movies and docos:


Compelling and disturbing is an accurate description of this documentary.  It revolves around the San Francisco Bay Bridge and the people who are determined to jump off it.  Literally the stood and filmed for a year people walking the bridge, some stopping, some jumping, some being hauled back over the bridge by worried citizens.  They took note of the jumpers and then went and interviewed the relatives and friends of the jumpers.  In one case it was a guy who stopped a female jumper, in another it was one of the jumpers who decided half way down he didn't want to die and changed his position on the way down,  so instead of dying he just shattered most of the bones in his body.   It was really weird watching these people walk across the bridge trying to pick the one who was going to jump - odd.  It also worried me that they were waiting for these people to jump to film it and not doing anything to stop them - icky ethical issues.  If you get the chance watch it.


Im a microbiologist - I inherently wanted to watch it.   A space shuttle crashes bringing a type of alien virus with it and it spreads through blood or body fluid contact (loved the vomiting into coffee pots at a CDC conference).  Enter Nicole Kidman, psychologist and her son (who by rare coincidence has had a type of chicken pox from which he almost died and so is now immune to the scary virus).   The virus enters the human host and become symbiotic once the human enters REM sleep, they then start talking and feeling as one and talk about being harmonious because there is no Other - so no fighting or wars just everyone working together minus the emotions.  The fight is to keep Nicole awake and her boy from his infected father.  Fluff movie but I liked it.

That's all.

S.

Okay I will bite

I haven't been very ranty lately - quite mellow actually.  The thing is at heart I'm a scientist, in particular I am a Microbiologist.  I am also a parent of a teenage girl.  Several headlines and news articles caught my attention this week and annoyed the bejesus enough out of me that I am going to rant.   This rant is pretty much about Immunisation and the media's role in demonizing common good sense science.  Here goes:

Once upon a time a doctor and his colleagues thought that they would publish an article on a study they had carried out.  This study had no real scientific basis, had a small co-hort of 12 individuals amongst other later revealed disturbing unethical bits and pieces going on, but came to the conclusion that the MMR vaccine causes autism.  This piece of research was held up by the media in general, autism conspiracists and general wackaloon's as stone cold solid evidence that the MMR vaccine was mad, bad and dangerous to give your beautiful babies.  Pity of it was that almost as soon as it was published it was called into question and it's findings refuted - did the media want to know? Nope - they ignored the majority of scientists and went with the one study that was the proverbial "whistleblower".   

The result of the media's ability to cause calamity where there was none is that a large number of reasonable, otherwise smart parents were conned into believing that the MMR vaccine could put their child at harm.  Whereas, in reality the truth is that the MMR vaccine is necessary to protect your child from some potentially nasty diseases.  Much like the meningitis jab - had a great conversation with someone last week who said cause the epidemic had "gone away" it wasn't necessary to vaccinate her child.  WTF?? Are you serious?? I mean really - what did you think caused the decrease in cases??  What happens when the now vaccinated cohort grows up and the kids who are being born now aren't vaccinated?  Quite possibly another epidemic - just because we controlled (note I say control not eliminate) this one doesn't mean it wont happen again.  Bacteria and viruses survive because they change and try to dodge the immune system - if you don't give the immune system a heads up - your child has a higher chance of becoming seriously sick and possibly dying.   Am I scaremongering?  I dont think so - I think that is it almost criminally negligent of parents not to vaccinate their children.  We as parents have a responsibility to provide kids with proper care and attention - part of that is ensuring they are healthy and have access to proper medical care.

The other current vaccination scaremongering is concerning Gardisil - the HPV vaccine or rather a HPV vaccine which has been associated (via the media not scientific publications) with nasty side effects like death.   HPV causes cervical cancer - it does.  Part of the problem is that there are many different genotypes of HPV - this vaccination protects against the most commonly associated strains.   So while it is conceivable you may get one of the rarer ones - you will be covered for the most common ones.  You can only do so much.

Am saving the other part of the rant for another time.

Suffice to say vaccinate your child - herd immunity will only take you so far.

S.